Related Research

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Current Research Applications


SemNExT is already being used to explore relationships between gene expression and brain formation, particularly in the presence of structural disorders such as Microcephaly. Semantically-informed and interactive visualizations (such as the one below, available at the SemNExT project demo page) are used to aid researchers in the medical community as they explore the causes of these conditions. A paper is currently in the works describing our approach and will be linked here soon.

Chord and Heat Map (CHEM) Diagram

Related Technologies


Below is a list of technologies that we've identified as being actively used, of similar interest, or of potential use to the SemNExT project going forward. Some of these are Tetherless World Constellation projects, others are production-ready libraries or are still in development.

Actively Used


  • Mobile Health: employed as a datasource for the current version of SemNExT; provides statistical results of accumulated biomedical sensor data

  • Repurposing Drugs with Semantics (ReDrugS): curated knowledge graph of protein-protein/protein-drug interactions; also a potential replacement for StringDB as a datasource

  • CSV2RDF4LOD: see project Github and wiki

Potential Extension Points


  • Semantic Workflows: Can be used to guide modelling of data flow and potentially compose analysis networks on the fly. YesWorkflow may meet such requirements and greatly augment the power of the framework if integrated properly.

  • Automated Python-to-OWL Conversion: There are numerous Python libraries that can potentially handle this task and would ease the developer's job when implementing a SemNExT project (see Seth and Owlready). If done properly, Python can be generated on-the-fly to carry out workflow-defined operations, using object representation of instance data that mirrors the semantics.