Study Cohort Ontology (SCO) and KG Creator

Ontology and Annotation Tool

SCO helps in the representation of descriptions of study populations in clinical trials including the various treatment arms, their measured characteristics and descriptive statistics of patients belonging to these arms.

We have also developed a tool to automatically create SCO-based KGs from Table 1s in clinical trial PDFs using NCBO BioAnnotator API.

  • Chari, S., Qi, M., Agu, N. N., Seneviratne, O., McCusker, J. P., Bennett, K. P., ... & McGuinness, D. L. (2019, October). Making study populations visible through knowledge graphs. In International Semantic Web Conference (pp. 53-68). Cham: Springer International Publishing.

  • Franklin, J. D., Chari, S., Foreman, M. A., Seneviratne, O., Gruen, D. M., McCusker, J. P., ... & McGuinness, D. L. (2020). Knowledge Extraction of Cohort Characteristics in Research Publications. In AMIA Annual Symposium Proceedings (Vol. 2020, p. 462). American Medical Informatics Association.