Jim McCusker works on Biomedical Semantics. His current
interests are data and provenance interoperability in life
sciences. He has worked as a software developer for 11 years in
bioinformatics, high performance computing, data mining, natural
language processing, and supply chain auditing.
James McCusker, Joshua A Phillips, Alejandra González Beltrán, Anthony Finkelstein, and Michael Krauthammer. “Semantic web data warehousing for caGrid.” BMC Bioinformatics 10, no. Suppl 10 (2009): S2. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2755823&tool=pmcentrez&rendertype=abstract.
Holford, Matthew E, James McCusker, Kei-Hoi Cheung, and Michael Krauthammer. “Analysis of Cancer Omics Data In A Semantic Web Framework.” In Proceedings of the 3rd International Workshop on Semantic Web Applications and Tools for the Life Sciences BerlinGermany December 810 2010, 1-15, 2010.
Halaban, Ruth, Wengeng Zhang, Antonella Bacchiocchi, Elaine Cheng, Fabio Parisi, Stephan Ariyan, Michael Krauthammer, James McCusker, Yuval Kluger, and Mario Sznol. “PLX4032, a selective BRAFV600E kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAFWT melanoma cells.” Pigment cell melanoma research 23, no. 2 (2010): 190-200. http://www.ncbi.nlm.nih.gov/pubmed/20149136.
McCusker J. "A Model for Comprehensive Biospecimen Lifecycles: From Clinic to Bench and Back" caBIG Tissue Banks and Pathology Tools Workspace Face to Face Meeting, Dec. 9-10 2009; caBIG Architecture Workspace Teleconference, Jan. 22, 2010; NCI LIMS Consortium Monthly Meeting, Feb. 22, 2009.
McCusker J. "Data Provenance and caGrid" caBIG Architecture & VCDE Joint Workspace Face to Face Meeting, May, 2009.
Krauthammer M., McCusker J. "MelaGrid: A Data Sharing Framework for Skin Cancer Research" caBIG Architecture & VCDE Joint Workspace Face to Face Meeting, May, 2009.
Open Source Projects
MAGE-TAB to MAGE-RDF: A tool to convert MAGE-TAB files, a common description format for microarray and gene expression data, into an RDF representation. http://magetab2rdf.googlecode.com
OWLtoSKOS: A tool for converting OWL ontologies into SKOS (http://www.w3.org/2004/02/skos) ontologies. This allows automated conversion of terminologies into a format that lets instance data directly reference the terms and concepts, simplifies the representations of existing controlled vocabularies and terminology hierarchies, and vastly improves inferencing performance. http://owltoskos.googlecode.com
Scholarships and Awards
Weissman Family Graduate Fellowship for 2009/2010.
Membership and Conference Chairs
Member of the World Wide Web Consortium (W3C) Provenance Incubator Group.
Publicity Co-Chair of International Provenance and Annotation Workshop (IPAW) 2010.
International Provenance and Annotations Workshop (IPAW) 2012
Journal of Web Semantics
Drug Discovery Today
Notable Class Projects
Semantic E-Science: Arunachalam S., Li X., McCusker J., Milack C. "Environmental Cleanup": Served as modeling expert and provided integration with a large number of existing ontologies.
Key Personnel on Grants and Contracts
caBIG Architecture Workspace Participant Contract, Yale University, FY 2008, renewed through FY 2009. Tissue Banks and Pathology Tools Architecture Workspace Guide to Mentors, Architecture representative on the Life Sciences Composite Architecture Team (LS-CAT), development of recommendations surrounding provenance standards within caBIG.