]> 2012-02-11T00:55:04-05:00 A Methodology for Determining Patients' Eligibility for Clinical Trials The task of determining patients' eligibility for clinical trials is knowledge and data intensive. In this paper, we present a model for the task of eligibility determination, and describe how a computer system can assist clinical researchers in performing that task. We describe qualitative and probabilistic approaches to computing and summarizing the eligibility status of potentially eligible patients. We compare the two approaches, and propose a synthesis that draws on the strength of each approach. The result of applying these techniques to a database of HIV-positive patient cases suggests that computer programs such as ours can increase the accrual rate of eligible patients into clinical trials. These methods also may be applied to the task of determining from electronic patient records whether practice guidelines apply in particular clinical situations. techreport November,1992 A Methodology for Determining Patients' Eligibility for Clinical Trials KSL-92-78 1992 Updated August '93. A Methodology for Determining Patients' Eligibility for Clinical Trials 1992 Year Title YES Process note Number Note November Month Ksl tr id Knowledge Systems, AI Laboratory Institution Has year Has where published Has title Has publishing details Has identifier Has author Bibtype Samson W. Tu and Carol A. Kemper and Nancy M. Lane and R. Carlson and Mark A. Musen Author Abstract KSL Technical Report Publication Technical Report