]> 2012-02-11T06:29:02-05:00 A Component-Based Architecture for Automation of Protocol-Directed Therapy The automation of protocol-based care requires reasoning about a patient's situation over time and about how the standard protocol plan can be adapted to address the patient's current clinical situation. The EON architecture brings together (1) a skeletal-planning reasoning method, ESPR, that can determine appropriate clinical interventions by instantiating an abstract protocol specification, (2) a temporal-reasoning system, RESUME, that can infer from time-stamped patient data higher-level, interval-based concepts, and (3) a historical database system, Chronus, that can perform temporal queries on a database of interval-based patient descriptions. The modular problem-solving elements of EON operate on knowledge bases of clinical protocols that clinicians enter into domain-specific knowledge-acquisition tools generated by the PROTEGE-II system. The EON architecture provides an integrated framework for development, execution, and maintenance of clinical-protocol knowledge bases. techreport 1995 A Component-Based Architecture for Automation of Protocol-Directed Therapy KSL-95-28 1995 Updated April. Medical Computer Science A Component-Based Architecture for Automation of Protocol-Directed Therapy 1995 Year Title NO Process note Number Note Ksl tr id Knowledge Systems, AI Laboratory Institution Has year Has where published Has title Has publishing details Has identifier Has author Bibtype Mark A. Musen and Samson W. Tu and Amar K. Das and Yuval Shahar Author Abstract KSL Technical Report Publication Technical Report