TW-2009-7 +, Semantic Web for Integrated Network Analysis in Biomedicine + redirect page
| Semantic web for integrated network analysis in biomedicine |
Bibtype
article
Has publishing details
10,2,177-192,2009
Has title
Semantic Web for Integrated Network Analysis in Biomedicine
Has tr id
TW-2009-07
Has where published
Briefings in Bioinformatics Advance
Has year
2009
Paper url
http://bib.oxfordjournals.org/cgi/content/abstract/10/2/177
Title
Semantic Web for Integrated Network Analysis in Biomedicine
Year
2009
Abstract
The Semantic Web technology enables integr … The Semantic Web technology enables integration of heterogeneous data on the World Wide Web by making the semantics of data explicit through formal ontologies. In this article, we survey the feasibility and state of the art of utilizing the Semantic Web technology to represent, integrate and analyze the knowledge in various biomedical networks. We introduce a new conceptual framework, semantic graph mining, to enable researchers to integrate graph mining with ontology reasoning in network data analysis. Through four case studies, we demonstrate how semantic graph mining can be applied to the analysis of disease-causal genes, Gene Ontology category cross-talks, drug efficacy analysis and herb-drug interactions analysis. lysis and herb-drug interactions analysis.
Author
Huajun Chen +, Li Ding +, Zhaohui Wu +, Tong Yu +, Lavanya Dhanapalan +, Jake Y. Chen +
Has author
Huajun Chen +, Li Ding +, Zhaohui Wu +, Tong Yu +, Lavanya Dhanapalan +, Jake Y. Chen +
Has identifier
TW-2009-07 +
Journal
Briefings in Bioinformatics Advance +
Number
2 +
Pages
177-192 +
Volume
10 +
Categories Journal Paper +, Publication +, TW Technical Report +
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