KSL-90-71 + redirect page
Knowledge-Based Simulation of DNA Metabolism: Prediction of Action and Envisionment of Pathways + Has identifier
Knowledge-Based Simulation of DNA Metabolism: Prediction of Action and Envisionment of Pathways + Ksl tr id
Knowledge-Based Simulation of DNA Metabolism: Prediction of Action and Envisionment of Pathways + Number
| Knowledge-Based Simulation of DNA Metabolism: Prediction of Action and Envisionment of Pathways |
Bibtype
techreport
Has publishing details
October,1990
Has title
Knowledge-Based Simulation of DNA Metabolism: Prediction of Action and Envisionment of Pathways
Has where published
KSL-90-71
Has year
1990
Title
Knowledge-Based Simulation of DNA Metabolism: Prediction of Action and Envisionment of Pathways
Year
1990
Abstract
We have developed a knowledge-based simula … We have developed a knowledge-based simulation of DNA metabolism that accurately predicts the actions of enzymes on DNA under a large number of environmental conditions. Previous simulations of enzyme systems rely predominantly on mathematical models. We use a frame-based representation to model enzymes, substrates and conditions. Interactions between these objects are expressed using production rules and an underlying truth maintenance system. The system performs rapid inference and can explain its reasoning. A graphical interface provides access to all elements of the simulation,including object representations and explanation graphs. Predicting enzyme action is the first step in the development of a large knowledge base to envision the metabolic pathways of DNA replication and repair. ic pathways of DNA replication and repair.
Address
Stanford, CA, USA +
Author
Adam Galper and David H. Millis and Douglas L. Brutlag +
Has author
Adam Galper and David H. Millis and Douglas L. Brutlag +
Has identifier
Knowledge-Based Simulation of DNA Metabolism: Prediction of Action and Envisionment of Pathways +
Institution
Knowledge Systems, AI Laboratory +
Ksl tr id
Knowledge-Based Simulation of DNA Metabolism: Prediction of Action and Envisionment of Pathways +
Month
October +
Number
Knowledge-Based Simulation of DNA Metabolism: Prediction of Action and Envisionment of Pathways +
Process note
NO +
Categories KSL Technical Report +, Publication +, Technical Report +
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