A Methodology for Determining Patients' Eligibility for Clinical Trials

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A Methodology for Determining Patients' Eligibility for Clinical Trials +  Has identifier

A Methodology for Determining Patients' Eligibility for Clinical Trials +  Ksl tr id

A Methodology for Determining Patients' Eligibility for Clinical Trials +  Number

A Methodology for Determining Patients' Eligibility for Clinical Trials

Bibtype  techreport

Has publishing details  November,1992

Has title  A Methodology for Determining Patients' Eligibility for Clinical Trials

Has where published  KSL-92-78

Has year  1992

Title  A Methodology for Determining Patients' Eligibility for Clinical Trials

Year  1992

Abstract  The task of determining patients' eligibil The task of determining patients' eligibility for clinical trials is knowledge and data intensive. In this paper, we present a model for the task of eligibility determination, and describe how a computer system can assist clinical researchers in performing that task. We describe qualitative and probabilistic approaches to computing and summarizing the eligibility status of potentially eligible patients. We compare the two approaches, and propose a synthesis that draws on the strength of each approach. The result of applying these techniques to a database of HIV-positive patient cases suggests that computer programs such as ours can increase the accrual rate of eligible patients into clinical trials. These methods also may be applied to the task of determining from electronic patient records whether practice guidelines apply in particular clinical situations. s apply in particular clinical situations.

Note  Updated August '93.

Author  Samson W. Tu and Carol A. Kemper and Nancy M. Lane and R. Carlson and Mark A. Musen +

Has author  Samson W. Tu and Carol A. Kemper and Nancy M. Lane and R. Carlson and Mark A. Musen +

Has identifier  A Methodology for Determining Patients' Eligibility for Clinical Trials +

Institution  Knowledge Systems, AI Laboratory +

Ksl tr id  A Methodology for Determining Patients' Eligibility for Clinical Trials +

Month  November +

Number  A Methodology for Determining Patients' Eligibility for Clinical Trials +

Process note  YES +

Categories  KSL Technical Report +, Publication +, Technical Report +

 

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