Semantic web for integrated network analysis in biomedicine

TW-2009-07

Publication article ( Edit )
type	Journal Paper
bibtype	article
Bibtex basics
author	Huajun Chen;Li Ding;Zhaohui Wu;Tong Yu;Lavanya Dhanapalan;Jake Y. Chen
title	Semantic Web for Integrated Network Analysis in Biomedicine
journal	Briefings in Bioinformatics Advance
volume	10
number	2
pages	177-192
year	2009
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abstract	The Semantic Web technology enables integration of heterogeneous data on the World Wide Web by making the semantics of data explicit through formal ontologies. In this article, we survey the feasibility and state of the art of utilizing the Semantic Web technology to represent, integrate and analyze the knowledge in various biomedical networks. We introduce a new conceptual framework, semantic graph mining, to enable researchers to integrate graph mining with ontology reasoning in network data analysis. Through four case studies, we demonstrate how semantic graph mining can be applied to the analysis of disease-causal genes, Gene Ontology category cross-talks, drug efficacy analysis and herb-drug interactions analysis.
paper url	http://bib.oxfordjournals.org/cgi/content/abstract/10/2/177

Abstract	The Semantic Web technology enables integr … The Semantic Web technology enables integration of heterogeneous data on the World Wide Web by making the semantics of data explicit through formal ontologies. In this article, we survey the feasibility and state of the art of utilizing the Semantic Web technology to represent, integrate and analyze the knowledge in various biomedical networks. We introduce a new conceptual framework, semantic graph mining, to enable researchers to integrate graph mining with ontology reasoning in network data analysis. Through four case studies, we demonstrate how semantic graph mining can be applied to the analysis of disease-causal genes, Gene Ontology category cross-talks, drug efficacy analysis and herb-drug interactions analysis. lysis and herb-drug interactions analysis.
Author	Huajun Chen +, Li Ding +, Zhaohui Wu +, Tong Yu +, Lavanya Dhanapalan +, and Jake Y. Chen +
Bibtype	article +
Has author	Huajun Chen +, Li Ding +, Zhaohui Wu +, Tong Yu +, Lavanya Dhanapalan +, and Jake Y. Chen +
Has identifier	TW-2009-07 +
Has publishing details	10,2,177-192,2009 +
Has title	Semantic Web for Integrated Network Analysis in Biomedicine +
Has tr id	TW-2009-07 +
Has where published	Briefings in Bioinformatics Advance +
Has year	2009 +
Journal	Briefings in Bioinformatics Advance +
Number	2 +
Pages	177-192 +
Paper url	http://bib.oxfordjournals.org/cgi/content/abstract/10/2/177 +
Title	Semantic Web for Integrated Network Analysis in Biomedicine +
Volume	10 +
Year	2009 +