A Methodology for Determining Patients' Eligibility for Clinical Trials

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Citation: Samson W. Tu and Carol A. Kemper and Nancy M. Lane and R. Carlson and Mark A. Musen. (1992) A Methodology for Determining Patients' Eligibility for Clinical Trials. In KSL-92-78, November,1992.

Publication techreport ( Edit )
type Technical Report
bibtype techreport
Bibtex basics
author Samson W. Tu and Carol A. Kemper and Nancy M. Lane and R. Carlson and Mark A. Musen
title A Methodology for Determining Patients' Eligibility for Clinical Trials
number KSL-92-78
institution Knowledge Systems, AI Laboratory
year 1992
month November
Bibtex more
note Updated August '93.
Access Paper
abstract The task of determining patients' eligibility for clinical trials is knowledge and data intensive. In this paper, we present a model for the task of eligibility determination, and describe how a computer system can assist clinical researchers in performing that task. We describe qualitative and probabilistic approaches to computing and summarizing the eligibility status of potentially eligible patients. We compare the two approaches, and propose a synthesis that draws on the strength of each approach. The result of applying these techniques to a database of HIV-positive patient cases suggests that computer programs such as ours can increase the accrual rate of eligible patients into clinical trials. These methods also may be applied to the task of determining from electronic patient records whether practice guidelines apply in particular clinical situations.

KSL Technical Report ID: KSL-92-78
Facts about A Methodology for Determining Patients' Eligibility for Clinical TrialsRDF feed
Abstract The task of determining patients' eligibil … The task of determining patients' eligibility for clinical trials is knowledge and data intensive. In this paper, we present a model for the task of eligibility determination, and describe how a computer system can assist clinical researchers in performing that task. We describe qualitative and probabilistic approaches to computing and summarizing the eligibility status of potentially eligible patients. We compare the two approaches, and propose a synthesis that draws on the strength of each approach. The result of applying these techniques to a database of HIV-positive patient cases suggests that computer programs such as ours can increase the accrual rate of eligible patients into clinical trials. These methods also may be applied to the task of determining from electronic patient records whether practice guidelines apply in particular clinical situations. s apply in particular clinical situations.
Author Samson W. Tu and Carol A. Kemper and Nancy M. Lane and R. Carlson and Mark A. Musen  +
Bibtype techreport  +
Has author Samson W. Tu and Carol A. Kemper and Nancy M. Lane and R. Carlson and Mark A. Musen  +
Has identifier KSL-92-78  +
Has publishing details November,1992  +
Has title A Methodology for Determining Patients' Eligibility for Clinical Trials  +
Has where published KSL-92-78  +
Has year 1992  +
Institution Knowledge Systems, AI Laboratory  +
Ksl tr id KSL-92-78  +
Month November  +
Note Updated August '93.
Number KSL-92-78  +
Process note YES  +
Title A Methodology for Determining Patients' Eligibility for Clinical Trials  +
Year 1992  +
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