Combining Physiologic Models and Symbolic Methods to Interpret Time-Varying Patient Data

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Citation: Michael G. Kahn and Lawrence M. Fagan and Lewis B. Sheiner. (1991) Combining Physiologic Models and Symbolic Methods to Interpret Time-Varying Patient Data. In KSL-91-63, 1991.

Publication techreport ( Edit )
type Technical Report
bibtype techreport
Bibtex basics
author Michael G. Kahn and Lawrence M. Fagan and Lewis B. Sheiner
title Combining Physiologic Models and Symbolic Methods to Interpret Time-Varying Patient Data
number KSL-91-63
institution Knowledge Systems, AI Laboratory
year 1991
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abstract This paper describes a methodology for representing and using medical knowledge about temporal relationships to infer the presence of clinical events that evolve over time. The methodology consists of three steps: (1) the incorporation of patient observations into a generic physiologic model, (2) the conversion of model states and predictions into domain-specific temporal abstractions, and (3) the transformation of temporal abstractions into clinically meaningful descriptive text. The first step converts raw observations to underlying model concepts, the second step identifies temporal features of the fitted model that have clinical interest, and the third step replaces features represented by model parameters and predictions into concepts expressed in clinical language. We describe a program, called TOPAZ, that uses this three-step methodology. TOPAZ generates a narrative summary of the temporal events foundin the electronic medical record of patients receiving cancer chemotherapy. A unique feature of TOPAZ is its use of numeric and symbolic techniques to perform different temporal reasoning tasks. Time is represented both as a continuous process and as a set of temporal intervals. These two temporal models differ in the temporal ontology they assume and in the temporal concepts they encode. Without multiple temporal models, this diversity of temporal knowledge could not be represented.

KSL Technical Report ID: KSL-91-63
Facts about Combining Physiologic Models and Symbolic Methods to Interpret Time-Varying Patient DataRDF feed
Abstract This paper describes a methodology for rep … This paper describes a methodology for representing and using medical knowledge about temporal relationships to infer the presence of clinical events that evolve over time. The methodology consists of three steps: (1) the incorporation of patient observations into a generic physiologic model, (2) the conversion of model states and predictions into domain-specific temporal abstractions, and (3) the transformation of temporal abstractions into clinically meaningful descriptive text. The first step converts raw observations to underlying model concepts, the second step identifies temporal features of the fitted model that have clinical interest, and the third step replaces features represented by model parameters and predictions into concepts expressed in clinical language. We describe a program, called TOPAZ, that uses this three-step methodology. TOPAZ generates a narrative summary of the temporal events foundin the electronic medical record of patients receiving cancer chemotherapy. A unique feature of TOPAZ is its use of numeric and symbolic techniques to perform different temporal reasoning tasks. Time is represented both as a continuous process and as a set of temporal intervals. These two temporal models differ in the temporal ontology they assume and in the temporal concepts they encode. Without multiple temporal models, this diversity of temporal knowledge could not be represented. mporal knowledge could not be represented.
Author Michael G. Kahn and Lawrence M. Fagan and Lewis B. Sheiner  +
Bibtype techreport  +
Has author Michael G. Kahn and Lawrence M. Fagan and Lewis B. Sheiner  +
Has identifier KSL-91-63  +
Has publishing details 1991  +
Has title Combining Physiologic Models and Symbolic Methods to Interpret Time-Varying Patient Data  +
Has where published KSL-91-63  +
Has year 1991  +
Institution Knowledge Systems, AI Laboratory  +
Ksl tr id KSL-91-63  +
Number KSL-91-63  +
Process note YES  +
Title Combining Physiologic Models and Symbolic Methods to Interpret Time-Varying Patient Data  +
Year 1991  +
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