]> 2012-05-27T23:31:35-04:00 A component-based architecture for automation of protocol-directed therapy The automation of protocol-based care requires reasoning about a patient'ssituation over time and about how the standard protocol plan can be adapted toaddress the patient's current clinical situation. The EON architecture bringstogether (1) a skeletal-planning reasoning method, ESPR, that can determineappropriate clinical interventions by instantiating an abstract protocolspecification, (2) a temporal-reasoning system, RESUME, that can infer fromtime-stamped patient data higher-level, interval-based concepts, and (3) ahistorical database system, Chronus, that can perform temporal queries on adatabase of interval-based patient descriptions. The modular problem-solvingelements of EON operate on knowledge bases of clinical protocols thatclinicians enter into domain-specific knowledge-acquisition tools generated bythe PROTEGE-II system. The EON architecture provides an integrated frameworkfor development, execution, and maintenance of clinical-protocol knowledgebases. techreport KSL-95-28 KSL-95-28 A Component-Based Architecture for Automation of Protocol-Directed Therapy KSL-95-28 1995 Year Tr id Title Computer science Tag Number Updated April. Medical Computer Science Note Key Knowledge Systems, AI Laboratory Institution Bibtype Yuval Shahar Amar K. Das Samson W. Tu Mark A. Musen Author Abstract KSL Technical Report Publication Technical Report