| Abstract
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The automation of protocol-based care requ … The automation of protocol-based care requires reasoning about a patient'ssituation over time and about how the standard protocol plan can be adapted toaddress the patient's current clinical situation. The EON architecture bringstogether (1) a skeletal-planning reasoning method, ESPR, that can determineappropriate clinical interventions by instantiating an abstract protocolspecification, (2) a temporal-reasoning system, RESUME, that can infer fromtime-stamped patient data higher-level, interval-based concepts, and (3) ahistorical database system, Chronus, that can perform temporal queries on adatabase of interval-based patient descriptions. The modular problem-solvingelements of EON operate on knowledge bases of clinical protocols thatclinicians enter into domain-specific knowledge-acquisition tools generated bythe PROTEGE-II system. The EON architecture provides an integrated frameworkfor development, execution, and maintenance of clinical-protocol knowledgebases. nance of clinical-protocol knowledgebases.
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