Experimental analysis of large belief networks for medical diagnosis

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abstract: We present an experimental analysis of two parameters that are important inknowledge engineering for large belief networks. We conducted the experimentson a network derived from the Internist-1 medical knowledge base. In thisnetwork, a generalization of the noisy-OR gate is used to model causalindependence for the multi-valued variables, and leak probabilities are used torepresent the nonspecified causes of intermediate states and findings. We studytwo network parameters, (1) the parameter governing the assignment ofprobability values to the network, and (2) the parameter denoting whether thenetwork nodes represent variables with two or more than two values. Theexperimental results demonstrate that the binary simplification computesdiagnoses with similar accuracy to the full multivalued network. We discuss theimplications of these parameters, as well as other network parameters, forknowledge engineering for medical applications.

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AbstractWe present an experimental analysis of two We present an experimental analysis of two parameters that are important inknowledge engineering for large belief networks. We conducted the experimentson a network derived from the Internist-1 medical knowledge base. In thisnetwork, a generalization of the noisy-OR gate is used to model causalindependence for the multi-valued variables, and leak probabilities are used torepresent the nonspecified causes of intermediate states and findings. We studytwo network parameters, (1) the parameter governing the assignment ofprobability values to the network, and (2) the parameter denoting whether thenetwork nodes represent variables with two or more than two values. Theexperimental results demonstrate that the binary simplification computesdiagnoses with similar accuracy to the full multivalued network. We discuss theimplications of these parameters, as well as other network parameters, forknowledge engineering for medical applications. edge engineering for medical applications.
AuthorMalcolm Pradhan  +, Gregory M. Provan  +, and Max Henrion  +
Bibtypetechreport  +
InstitutionKnowledge Systems, AI Laboratory  +
KeyKSL-94-36  +
MonthMay  +
NoteMedical Computer Science  +
NumberKSL-94-36  +
TagComputer science  +
TitleExperimental Analysis of Large Belief Networks for Medical Diagnosis  +
Tr idKSL-94-36  +
Year1994  +
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