A hybrid classifier for automated radiologic diagnosis: preliminary results and clinical applications

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abstract: We describe the design, implementation, and preliminary evaluation of acomputer system to aid clinicians in the interpretation of cranial magnetic-resonance (MR) images. The system classifies normal and pathologic tissues ina test set of MR scans with high accuracy. It also provides a simple, rapidmeans whereby an unassisted expert may reliably label an image with his bestjudgment of its histologic composition, yielding a gold-standard image; thisstep facilitates objective evaluation of classifier performance. This systemconsists of a preprocessing module; a semiautomatic, reliable procedure forobtaining objective estimates of an expert's opinion of an image's tissuecomposition; a classification module based on a combination of the maximum-likelihood (ML) classifier and the ISODATA unsupervised-clustering algorithm;and an evaluation module based on confusion-matrix generation. The algorithmsfor classifier evaluation and gold-standard acquisition are advances overprevious methods. Furthermore, the combination of a clustering algorithm anda statistical classifier provides advantages not found in systems using eithermethod alone.

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AbstractWe describe the design, implementation, an We describe the design, implementation, and preliminary evaluation of acomputer system to aid clinicians in the interpretation of cranial magnetic-resonance (MR) images. The system classifies normal and pathologic tissues ina test set of MR scans with high accuracy. It also provides a simple, rapidmeans whereby an unassisted expert may reliably label an image with his bestjudgment of its histologic composition, yielding a gold-standard image; thisstep facilitates objective evaluation of classifier performance. This systemconsists of a preprocessing module; a semiautomatic, reliable procedure forobtaining objective estimates of an expert's opinion of an image's tissuecomposition; a classification module based on a combination of the maximum-likelihood (ML) classifier and the ISODATA unsupervised-clustering algorithm;and an evaluation module based on confusion-matrix generation. The algorithmsfor classifier evaluation and gold-standard acquisition are advances overprevious methods. Furthermore, the combination of a clustering algorithm anda statistical classifier provides advantages not found in systems using eithermethod alone. found in systems using eithermethod alone.
AuthorEdward Herskovits  +
Bibtypetechreport  +
InstitutionKnowledge Systems, AI Laboratory  +
KeyKSL-90-46  +
NumberKSL-90-46  +
TagComputer science  +
TitleA Hybrid Classifier for Automated Radiologic Diagnosis: Preliminary Results and Clinical Applications  +
Tr idKSL-90-46  +
Year1990  +
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